Approach


  • Marmoset (MAR) antigen (cytokine, hormone) design, plasmid development and antigen production.
  • Immunization of mice and serology analysis.
  • Hybridoma production and monoclonal antibody (mAb) screening.
  • Small scale mAb production and purification.
  • Identification of optimal mAb pairs for immunoassays and single mAbs for Flow Cytometry.
  • Subcloning or sequencing, small-scale production and purification of optimal mAbs.
  • Large scale mAb production, purification, conjugation, QC, benchmarking (if possible), titration, stability tests, ELISA standard development.
  • Validation with MAR samples in relevant assays.
  • Validation with owl monkey (OWL) and squirrel monkey (SQM) samples in relevant assays.
  • Availability of validated mAbs for researchers.